Iria: Zeiram the Animation (1993) IMDb
An interstellar empire appoints Hunters to deal with various dangers. Such a Hunter, Gren, and his young “sister”/apprentice Iria, encounter an almost immortal creature. Gren attempts a suicidal attack against it, whereafter Iria is left to fend for herself. She makes some friends during the long mutual hunt through exotic environments, and makes heavy use of gadgets.
Fantasy/SF action. 80% style over substance. Based on a live-action movie.